A linked physiologically based pharmacokinetic model for hydroxychloroquine and metabolite desethylhydroxychloroquine in SARS-CoV-2(-)/(+) populations

By sjmartinez • April 30, 2023

Steinbronn C, Chhonker YS, Stewart J, Leingang H, Heller KB, Krows ML, Paasche-Orlow M, Bershteyn A, Stankiewicz Karita HC, Agrawal V, Laufer M, Landovitz R, Wener M, Murry DJ, Johnston C, Barnabas RV, Arnold SLM. A linked physiologically based pharmacokinetic model for hydroxychloroquine and metabolite desethylhydroxychloroquine in SARS-CoV-2(-)/(+) populations. Clin Transl Sci. 2023 Apr 29. doi: 10.1111/cts.13527. Epub ahead of print. PMID: 37118968.

Tags: CARE Unit, Infectious Diseases, Publications

Features of HIV Infection in the Context of Long-Acting Cabotegravir Preexposure Prophylaxis

Landovitz RJ, Delany-Moretlwe S, Fogel JM, Eshleman SH, Marzinke MA, Piwowar-Manning E, Richardson P, Halvas EK, Mellors JW, Persaud D, Kofron R, McCauley M, Rose[...]

Arrhythmogenic effects of acute electronic cigarette compared to tobacco cigarette smoking in people living with HIV

Ruedisueli I, Shi K, Lopez S, Gornbein J, Middlekauff HR. Arrhythmogenic effects of acute electronic cigarette compared to tobacco cigarette smoking in people living with[...]

Evaluation of Xpert point-of-care assays for detection of HIV infection in persons using long-acting cabotegravir for pre-exposure prophylaxis

Fogel JM, Piwowar-Manning E, Moser A, Hill T, Ahmed S, Cummings V, Mostafa HH, Wang Z, Jennings A, Gallardo-Cartagena JA, Figueroa MI, St Clair M,[...]