A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes

By sjmartinez • March 18, 2023

Wilder CL, Lefaudeux D, Mathenge R, Kishimoto K, Zuniga Munoz A, Nguyen MA, Meyer AS, Cheng QJ, Hoffmann A. A stimulus-contingent positive feedback loop enables IFN-β dose-dependent activation of pro-inflammatory genes. Mol Syst Biol. 2023 Mar 17:e11294. doi: 10.15252/msb.202211294. Epub ahead of print. PMID: 36929731.

Tags: IFN-β, Infectious Diseases, inflammatory response, ISGF3, Publications, signaling dynamics, stimulus-contingent positive feedback loop

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