Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies

By sjmartinez • March 14, 2023

Acin-Perez R, Benincá C, Fernandez Del Rio L, Shu C, Baghdasarian S, Zanette V, Gerle C, Jiko C, Khairallah R, Khan S, Rincon Fernandez Pacheco D, Shabane B, Erion K, Masand R, Dugar S, Ghenoiu C, Schreiner G, Stiles L, Liesa M, Shirihai OS. Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies. EMBO J. 2023 Mar 13:e111699. doi: 10.15252/embj.2022111699. Epub ahead of print. PMID: 36912136.

Tags: ATP hydrolysis, ATPase Inhibitor (ATPIF1), Complex V, Endocrinology, epicatechin, muscular dystrophy, Publications

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