Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies

By sjmartinez • March 14, 2023

Acin-Perez R, Benincá C, Fernandez Del Rio L, Shu C, Baghdasarian S, Zanette V, Gerle C, Jiko C, Khairallah R, Khan S, Rincon Fernandez Pacheco D, Shabane B, Erion K, Masand R, Dugar S, Ghenoiu C, Schreiner G, Stiles L, Liesa M, Shirihai OS. Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies. EMBO J. 2023 Mar 13:e111699. doi: 10.15252/embj.2022111699. Epub ahead of print. PMID: 36912136.

Tags: ATP hydrolysis, ATPase Inhibitor (ATPIF1), Complex V, Endocrinology, epicatechin, muscular dystrophy, Publications

Impaired AMPK control of alveolar epithelial cell metabolism promotes pulmonary fibrosis

Rodríguez LR, Alysandratos KD, Katzen J, Murthy A, Roque Barboza W, Tomer Y, Bui S, Acín-Pérez R, Petcherski A, Minakin K, Carson P, Iyer S,[...]

A Case of Endosteal Hyperostosis Caused by a Mutation of the Low-Density Lipoprotein Receptor-Related Protein 5 (LRP5) Gene

Beshay LH. A Case of Endosteal Hyperostosis Caused by a Mutation of the Low-Density Lipoprotein Receptor-Related Protein 5 (LRP5) Gene. Cureus. 2025 May 30;17(5):e85100. doi:[...]

Pharmacological Characterization of Vampire Bat-Derived CGRP at the Human CGRP Receptor in the Xenopus oocyte system

Carleer K, Raval K, Tudzarova S, Tytgat J. Pharmacological Characterization of Vampire Bat-Derived CGRP at the Human CGRP Receptor in the Xenopus oocyte system. Toxicon.[...]