Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies

By sjmartinez • March 14, 2023

Acin-Perez R, Benincá C, Fernandez Del Rio L, Shu C, Baghdasarian S, Zanette V, Gerle C, Jiko C, Khairallah R, Khan S, Rincon Fernandez Pacheco D, Shabane B, Erion K, Masand R, Dugar S, Ghenoiu C, Schreiner G, Stiles L, Liesa M, Shirihai OS. Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies. EMBO J. 2023 Mar 13:e111699. doi: 10.15252/embj.2022111699. Epub ahead of print. PMID: 36912136.

Tags: ATP hydrolysis, ATPase Inhibitor (ATPIF1), Complex V, Endocrinology, epicatechin, muscular dystrophy, Publications

Deletion of PTP1B in cardiomyocytes alters cardiac metabolic signaling to protect against cardiomyopathy induced by a high-fat diet

Sun Y, Mishra AK, Chanrasekhar V, Door M, Kessinger CW, Xu B, Tang P, Gao Y, Kamli-Salino S, Nelson K, Delibegovic M, Abel ED, Kirk[...]

Exercise training remodels inter-organ endocrine networks

Ahn C, Hevener AL, Goodyear LJ, Bodine SC, Esser KA, Seldin MM, Sparks LM. Exercise training remodels inter-organ endocrine networks. Mol Metab. 2025 Jul 21:102219.[...]

Glucagon-Like Peptide-1 Receptor Agonists and Incidence of Dementia Among Older Adults With Type 2 Diabetes : A Target Trial Emulation

Inoue K, Saliba D, Gotanda H, Moin T, Mangione CM, Klomhaus AM, Tsugawa Y. Glucagon-Like Peptide-1 Receptor Agonists and Incidence of Dementia Among Older Adults[...]