A phase II, multicenter, open-label, randomized trial of pegfilgrastim for patients with alcohol-associated hepatitis

By sjmartinez • October 22, 2022

Tayek JA, Stolz AA, Nguyen DV, Fleischman MW, Donovan JA, Alcorn JM, Chao DC, Asghar A, Morgan TR; Southern California Alcoholic Hepatitis (SCAH) Consortium. A phase II, multicenter, open-label, randomized trial of pegfilgrastim for patients with alcohol-associated hepatitis. EClinicalMedicine. 2022 Oct 12;54:101689. doi: 10.1016/j.eclinm.2022.101689. PMID: 36267499; PMCID: PMC9576807.

Tags: ACLF, acute kidney injury, acute on chronic liver failure, AH, AKI, alcohol-related hepatitis, Alcoholic hepatitis, common terminology criteria for adverse events, CTCAE, data safety monitoring board, DF, discriminant function, DSMB, FDA, follow-up, food and drug administration, FU, GCSF, General Internal Medicine, granulocyte colony stimulating factor, Harbor UCLA, hepatorenal syndrome, HIV, HRS, human immunodeficiency virus, INR, international normalized ratio, national institute on alcohol abuse and alcoholism, NIAAA, Pegfilgrastim, Phase II, Publications, Randomized clinical trial, SD, SOC, standard deviation, standard of care, WBC, white blood cell count

First comparison between artificial intelligence-guided coronary computed tomography angiography versus single-photon emission computed tomography testing for ischemia in clinical practice

Cho GW, Sayed S, D'Costa Z, Karlsberg DW, Karlsberg RP. First comparison between artificial intelligence-guided coronary computed tomography angiography versus single-photon emission computed tomography testing[...]

Inequities in Access to Mental Health Services Among Asian American, Native Hawaiian, and Pacific Islander Medicaid Enrollees

Nguyen KH, Oh EG, Ðoàn LN, Chu CT, Banawa RA, Oronce CIA, Choy CC, Zhou S. Inequities in Access to Mental Health Services Among Asian[...]

Increasing Diversity in the Nutrition, Obesity, and Diabetes Biomedical Workforce: The BRIDGES Consortium

Newton RL Jr, Katzmarzyk PT, Duru OK, Lee A, Irwin A, Mangione CM, Morone NE, Ongeri EM, Shaikh SR, Stanford FC, Stanley TL, Truesdale KP;[...]