Robust therapeutic effects on COVID-19 of novel small molecules: Alleviation of SARS-CoV-2 S protein induction of ACE2/TMPRSS2, NOX2/ROS, and MCP-1

By sjmartinez • October 4, 2022

Youn JY, Wang J, Li Q, Huang K, Cai H. Robust therapeutic effects on COVID-19 of novel small molecules: Alleviation of SARS-CoV-2 S protein induction of ACE2/TMPRSS2, NOX2/ROS, and MCP-1. Front Cardiovasc Med. 2022 Sep 15;9:957340. doi: 10.3389/fcvm.2022.957340. PMID: 36187008; PMCID: PMC9520320.

Tags: acute respiratory distress syndrome (ARDS), Cardiology/Epi, covid-19, endothelial dysfunction, NADPH oxidase isoform 2 (NOX2), Publications, SARS-CoV-2

Artificial-intelligence-assisted CCTA quantifies sex differences in coronary atherosclerotic burden at low atheroma volumes

D'Costa Z, Karlsberg RP, Cho GW. Artificial-intelligence-assisted CCTA quantifies sex differences in coronary atherosclerotic burden at low atheroma volumes. Int J Cardiol Heart Vasc. 2025[...]

Genetic and sex-specific regulation of mitochondrial function in gonadal and inguinal adipose tissue

Kaminska D, Pan C, Vergnes L, Ro A, Ulaganathan G, Lusis AJ. Genetic and sex-specific regulation of mitochondrial function in gonadal and inguinal adipose tissue.[...]

A call for transparency, improved reporting, and interpretation of trials using surrogate end points in cardiac electrophysiology

Tereshchenko LG, Manyara AM, Ciani O, Sodeke SO, Bradford CN, Santangeli P, Kapadia SR, Wazni O, Narayan SM, Chugh SS, Bilchick K, Huizar JF, Vaseghi[...]