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October 24th, 2016

Blood-cancer research, patients focus of “Light The Night” walk

By Roxanne Moster

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With invitations to so many worthy medical causes and events, it becomes a difficult decision to figure out how to devote your time and energy.  But a colleague who was diagnosed with a blood cancer gave me a laser focus on an upcoming event.

Like my treasured co-worker, Jassmine Ahumada’s 7-year-old son, Rey, should be enjoying life to the fullest.  He should be running, jumping and playing outside like most other children his age. Instead, he’s fighting leukemia and “stuck in a bubble,” says his mom, an admissions clerk at UCLA Medical Center, Santa Monica. “That word, ‘cancer,’” she adds. “We need to put an end to it.”

With that as a goal, UCLA Health became a presenting sponsor of the Leukemia & Lymphoma Society’s Oct. 22 “Light the Night Walk” at L.A. Live in a mission to raise research funds to find cures for blood cancers.  More than 60 teams composed of hundreds of UCLA Health staff members, patients, including many cancer survivors, family members, researchers and community members participated by carrying red, white or yellow lanterns in support of loved ones.

“Over the years, the society has funded about 50 UCLA researchers with almost $10 million, and its support has been vital to the development of many treatment breakthroughs, including Gleevec, a pill for a common form of adult leukemia that has dramatically improved five-year survival rates,” said Johnese Spisso, president of UCLA Health and corporate walk chair for the Los Angeles event.

Jassmine says of her son, “He’s the strongest little boy you’ve ever seen. Every month he has to have a spinal puncture for his chemotherapy. When new children come to the clinic frightened and crying, Rey offers comfort and reassurance. He shows them his own port and explains that they don’t need to be afraid and that it won’t hurt.” Funds raised from the “Light the Night” will also help improve patient access to treatment and bolster services for patients and their families.

Rey with the Laker Girls

Rey with the Laker Girls

Rey, accompanied by Jassmine and her husband, joined other cancer survivors in carrying a white lantern, signifying the power of research and hope for a cure. Supporters carried red lanterns and individuals who commemorated a loved one lost to cancer carried yellow lanterns. I carried a red one for my friend.

Another UCLA Health employee, Martin Lingard, also walked at Light the Night with a white lantern. Lingard, a four-and-one-half-year lymphoma survivor, said he was “proud and pleased to be carrying a white lantern” to raise awareness and research funds that will lead to better therapies and cancer-fighting drugs with fewer damaging side effects.

“It was an amazing event,” said Lingard.  “It was my first time walking ‘Light the Night’ and it was wonderful to see so many people come out for an amazing cause.  I was also heartened to see white lanterns of survivors walking like me. It gave me renewed hope and energy to keep fighting for this important cause.”

The American Society of Hematology explains on its website that blood cancers affect the production and function of the body’s normal blood cells. Most of these cancers start in the bone marrow where blood is produced. Stem cells in the bone marrow mature and develop into three types of blood cells: red blood cells, white blood cells, or platelets. In most blood cancers, the normal blood cell development process is interrupted by uncontrolled growth of an abnormal type of blood cell. These abnormal blood cells, or cancerous cells, prevent the blood from performing many of its functions, like fighting off infections or preventing serious bleeding.

According to UCLA blood cancer researcher Dr. John Timmerman, the Leukemia & Lymphoma Society is the only organization that focuses completely on blood cancers. “They want to advocate for new research and bring exciting cures for patients with all different types of blood cancer,” said Timmerman, professor of medicine in the division of hematology and oncology at UCLA Health.

Statistics from the Leukemia & Lymphoma Society:

  • Approximately every 3 minutes someone in the United States is diagnosed with a blood cancer.
  • An estimated combined total of 171,550 people in the US are expected to be diagnosed with leukemia, lymphoma or myeloma in 2016.
  • New cases of leukemia, lymphoma and myeloma are expected to account for 10.2 percent of the estimated 1,685,210 new cancer cases diagnosed in the U.S. in 2016.

Timmerman says the future holds promise in that it may not be long before immunotherapies begin to take the place of chemotherapy in some cases. “For some lymphomas, we are seeing prolonged remissions with immunotherapies such as checkpoint inhibitors or engineered T cells.  Combining immunotherapy with other targeted therapies is also showing exciting results in the laboratory and early clinical trials. In some cases, these treatments are looking to be just as effective as traditional chemotherapy,” he says.

Immunotherapy is emerging as the “fourth pillar” of cancer treatment, joining surgery, radiation and chemotherapy, according to UCLA researchers. That means that cancer patients today, perhaps more than ever before, need to ask questions about emerging treatments, even therapies that are still in clinical trials. “In many communities, doctors are not aware of how fast this is moving,” Timmerman notes. “Patients need to be aggressive in seeking out these new treatments that are available in clinical trials.”

Tags: adult leukemia, American Society of Hematology, blood cancer, blood cells, bone marrow, Cancer, cancer, cancer survivors, cancer treatment, chemotherapy, clinical trials, Dr. John Timmerman, engineered T cells, Gleevec, hematology, immunotherapies, joining surgery, Leukemia, leukemia, Leukemia & Lymphoma Society, Light The Night, Light the Night Walk, lymphoma, lymphoma survivor, myeloma, News & Insights, oncology, platelets, radiation, red blood cells, research, spinal puncture, survival rates, UCLA Medical Center Santa Monica, white blood cells

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